Engineered micro-scale human tissue models for controlling and understanding cellular interactions in human diseases and drug responses
The research in µTE lab focuses on engineering multi-scale human tissue models for controlling and understanding cellular interactions in human diseases and drug responses. Our approach is to interface tissue engineering with microtechnologies, such as microfluidics and microarrays, to incorporate biological complexity into quantitative screening platforms. Through this effort, we expect to capture more complex multi-cellular phenotypes and interactions to bridge between simplistic single cell-based assays and animal studies.
to recreate artificial environments that can guide embryonic tissue patterning processes during early neurodevelopment.
that enable us to control, perturb and measure cell-cell interactions with increased precision and translate them into applications in drug discovery.
for modulating stem cell fates using fluid shear stress and substrate stiffness and topographies.